Spinach & Artichoke Chicken Bake

Featured in: Rustic Weekend Comfort Recipes

This creamy spinach and artichoke chicken bake combines tender, seasoned chicken breasts with a rich topping of sautéed spinach, artichoke hearts, Greek yogurt, and melted cheese. The dish comes together in just 45 minutes total—15 minutes prep and 30 minutes baking—making it ideal for busy weeknights. The topping gets golden and bubbly in the oven while the chicken cooks through to a safe internal temperature.

This main dish serves four and works wonderfully with rice, quinoa, or a fresh green salad on the side. It's naturally high in protein and can be made gluten-free, though always verify cheese labels for cross-contamination if you have sensitivities. Leftovers keep well refrigerated for up to three days, making it great for meal prep.

Updated on Tue, 20 Jan 2026 16:35:00 GMT
Golden-brown baked chicken breasts smothered in a creamy spinach and artichoke topping, served hot from the oven. Save
Golden-brown baked chicken breasts smothered in a creamy spinach and artichoke topping, served hot from the oven. | saffronbrook.com

The smell of bubbling cheese and spinach takes me back to my tiny apartment kitchen where I first discovered that the creamy dip everyone fought over at parties could actually become dinner. I had leftover spinach and chicken that needed using, and somewhere between skepticism and hunger, this bake was born. Now it is the dinner my family actually cheers for when they walk through the door.

Last Tuesday my friend Sarah stayed late for what was supposed to be a quick dinner and ended up scraping the baking dish clean with her fork. She texted me the next morning asking for the recipe because her husband kept talking about the chicken with the dip on top. There is something about that combination of tender meat and tangy topping that makes people ask for seconds.

Ingredients

  • Chicken breasts: Pound them to even thickness so they cook at the same rate
  • Fresh spinach: Baby spinach wilts quickly and has no tough stems to remove
  • Artichoke hearts: Canned ones work perfectly here, just give them a good squeeze to remove excess liquid
  • Greek yogurt: Whole milk version gives the best creamy texture but you can use what you have
  • Garlic: Fresh minced cloves make a difference over powder
  • Mozzarella: Shredded from a block melts better than pre-shredded bags
  • Parmesan: Adds that salty umami punch that makes the topping sing
  • Oregano and red pepper flakes: These two balance the richness with warmth and subtle heat

Instructions

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Get your oven ready:
Preheat to 400°F and give your baking dish a quick coat of oil so nothing sticks
Season the chicken:
Sprinkle both sides with salt and pepper then lay them in the dish without overlapping
Build the flavor base:
Warm olive oil in a skillet, cook the garlic for thirty seconds until you can smell it, then toss in the spinach until it just collapses
Mix the topping:
Combine the wilted spinach with artichokes, Greek yogurt, both cheeses, oregano, and red pepper flakes in a bowl
Top and bake:
Pile the mixture evenly over each chicken breast and bake until the chicken reaches 165°F and the cheese is golden and bubbling
Let it rest:
Five minutes on the counter lets the juices redistribute so each bite stays moist
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Create smooth frozen drinks, slushies, and frappés for desserts and parties using juices, coffee, or wine.
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A close-up of the Spinach & Artichoke Chicken Bake with melted cheese and wilted greens. Save
A close-up of the Spinach & Artichoke Chicken Bake with melted cheese and wilted greens. | saffronbrook.com

Sunday dinner at my parents house has rotated around a few reliable favorites but this one earned a permanent spot on the rotation. My dad who usually complains about healthy anything went back for thirds and my mom asked if we could make it a weekly thing. Watching them enjoy something that started as a kitchen experiment made me feel like maybe I am getting the hang of this cooking thing after all.

Making It Your Own

Once you have the basic method down this recipe becomes a canvas. I have swapped in turkey cutlets, added sun-dried tomatoes for extra tang, and even thrown in sautéed mushrooms when the garden produced more than we could eat. The topping works on almost anything and bakes up beautifully every single time.

What To Serve With It

A simple green salad with bright vinaigrette cuts through the richness beautifully. Sometimes I roast asparagus alongside the chicken during the last fifteen minutes so everything comes out together. Rice or quinoa soaked in the extra sauce from the bottom of the pan might be my favorite way to enjoy the leftovers for lunch the next day.

Storage And Reheating

This keeps remarkably well in the refrigerator for three days and actually tastes better the second night when the flavors have had time to settle together. Reheat gently in the microwave at fifty percent power so the yogurt does not separate. The topping stays surprisingly creamy if you do not rush it.

  • Freeze individual portions before baking for busy weeks
  • Add ten minutes to the bake time if cooking from frozen
  • Let frozen portions thaw overnight in the refrigerator first
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Juicy chicken breasts topped with a tangy spinach and artichoke mixture, perfect for a comforting weeknight dinner. Save
Juicy chicken breasts topped with a tangy spinach and artichoke mixture, perfect for a comforting weeknight dinner. | saffronbrook.com

Some recipes become favorites because they are fancy and impressive but this one wins because it is honest, satisfying food that brings people back to the table. That is the kind of cooking I want to be known for.

Saffron Brook Recipe Q&As

How do I know when the chicken is fully cooked?

Use a meat thermometer to check that the internal temperature reaches 165°F (74°C) at the thickest part of the chicken breast. This ensures the chicken is safe to eat and perfectly cooked through.

Can I prepare this dish ahead of time?

Yes, you can assemble the dish up to 8 hours in advance. Cover it with plastic wrap and refrigerate. Add 5-10 minutes to the baking time since you'll be starting from a cold temperature.

What can I substitute for Greek yogurt?

You can use sour cream, ricotta cheese, or a combination of cream cheese and milk for a similar creamy texture. For a lighter option, use 2% Greek yogurt or mix it with a bit of cottage cheese.

Is this dish truly gluten-free?

As written, yes. However, always check your cheese labels for potential cross-contamination during manufacturing. Some aged cheeses and processed varieties may contain gluten, so verify with the manufacturer if you have celiac disease or gluten sensitivity.

What are some good side dish pairings?

Serve with steamed rice, fluffy quinoa, roasted vegetables, or a crisp green salad to balance the richness of the creamy topping. Garlic bread or crusty rolls also pair nicely for soaking up any extra sauce.

Can I use frozen spinach instead of fresh?

Yes, use about 1 cup of frozen spinach (thawed and squeezed dry to remove excess moisture). This works just as well as fresh spinach and can even be more convenient for meal planning.

Spinach & Artichoke Chicken Bake

Tender chicken breasts baked with creamy spinach, artichoke, and cheese topping. Easy, comforting weeknight dinner ready in 45 minutes.

Prep time
15 mins
Cook time
30 mins
Time required
45 mins
Created by Ariana Brooks


Skill Level Easy

Cuisine Type American

Serves 4 Portions

Dietary notes Wheat-Free, Low in Carbs

Ingredient List

Chicken

01 4 boneless, skinless chicken breasts, approximately 1.5 pounds
02 1/2 teaspoon kosher salt
03 1/4 teaspoon freshly ground black pepper

Spinach & Artichoke Topping

01 1 tablespoon olive oil
02 2 cups fresh baby spinach, roughly chopped
03 1 can (14 ounces) artichoke hearts, drained and coarsely chopped
04 2 cloves garlic, minced
05 1 cup plain Greek yogurt, preferably whole milk
06 1/2 cup shredded mozzarella cheese
07 1/4 cup grated Parmesan cheese
08 1/4 teaspoon dried oregano
09 1/4 teaspoon crushed red pepper flakes, optional

How to Make

Step 01

Prepare the baking dish and season chicken: Preheat oven to 400°F. Lightly grease a 9x13-inch baking dish. Season chicken breasts with salt and pepper, then arrange in a single layer in the prepared dish.

Step 02

Sauté garlic and wilt spinach: Heat olive oil in a skillet over medium heat. Add minced garlic and sauté for 30 seconds until fragrant. Add chopped spinach and cook until just wilted, approximately 2 minutes.

Step 03

Combine topping ingredients: In a mixing bowl, combine the sautéed spinach, chopped artichoke hearts, Greek yogurt, mozzarella, Parmesan, oregano, and crushed red pepper flakes if desired. Mix thoroughly until well combined.

Step 04

Apply topping to chicken: Spread the spinach and artichoke mixture evenly over the chicken breasts, covering them completely.

Step 05

Bake until cooked through: Bake for 25 to 30 minutes, or until chicken reaches an internal temperature of 165°F and the topping is golden and bubbly.

Step 06

Rest and serve: Remove from oven and let rest for 5 minutes before serving.

Equipment Needed

  • 9x13-inch baking dish
  • Skillet
  • Mixing bowl
  • Knife and chopping board
  • Measuring cups and spoons

Allergy advice

Review ingredients for potential allergens and reach out to a healthcare expert if unsure.
  • Contains dairy: Greek yogurt, mozzarella cheese, and Parmesan cheese.
  • May contain eggs if using egg-enriched cheese variants.
  • Verify all ingredient labels for potential gluten cross-contamination if sensitivity exists.

Nutrition per serving

Nutritional details are for reference only and shouldn't replace professional advice.
  • Energy: 325
  • Total fat: 11 g
  • Carbohydrates: 7 g
  • Proteins: 48 g